Divisional games often bring out the best in Seattle, even when they’re not the deeper team on paper. That’s why this matchup is always tricky for bettors. The 49ers are the more complete roster, but Seattle plays with enough unpredictability at home to make this a compelling betting opportunity.
San Francisco’s offense thrives when they can run the ball effectively and set up play-action. Their biggest issue has been offensive line health. When they are missing key pieces, defenses have found ways to push pressure inside, disrupting timing.
Seattle has been inconsistent, especially defensively, but they do play with emotion in front of their home crowd. Their pass rush is inconsistent but capable of big moments. If they can keep the game within one score early, this matchup can become much tighter than the line may suggest.
The total deserves attention. San Francisco games can get low-scoring when they control tempo, but if Seattle scores early, the game opens up quickly.
The market often overvalues San Francisco in divisional contests, which makes Seattle an intriguing underdog.
Prediction: Seahawks +6.5
